Detoxification and adaptation mechanisms of <i>Trichoderma atroviride</i> to antifungal agents

Abstract Filamentous fungi are crucial for recycling of organic material in nature. In natural habitats, they cope with many stress factors and therefore their adaptation ability to various conditions is very high. Trichoderma sp., used agriculture as biocontrol agent, exposed a variety toxic molecules including pesticides fungicides. They have fight using mechanisms known the response. Adaptation stress, especially chemical not well studied environmental fungal strains. Moreover, process presents risk resistance mechanism induction antifungal agents. Such resistant strains could be spread environment. This work aims contribute knowledge throughout kingdom. Transcriptional response ABC transporters, main detoxification efflux pumps subfamily B G presence agents, shown. On other hand, azoles most commonly structures clinical practice agriculture, changes important ergosterol biosynthesis genes result exposure structure highlighted.